Noninvasive imaging modalities such as CT and MRI provide unprecedented views of the human body and are a routine tool in medicine. However, they only provide high resolution structural information. Alternative tools such as diffuse optical tomography (DOT) can provide critical functional information; such as whether tissue or a tumor is oxygen starved. DOT employs near infrared light to penetrate human tissue.
Hybrid imaging offers a way to improve spatial resolution. High resolution structural images provide boundary conditions, also known as structural priors, to remove the ambiguity that scattering introduces and provide DOT images with unprecedented resolution.
RMD is involved in clinical collaborations to explore two forms of hybrid imaging:
In collaboration with scientists at Dartmouth College and the Massachusetts General Hospital, RMD is developing hybrid imaging techniques that augment the structural information obtained by MRI with functional information obtained by DOT.